Emergence of MERS-CoV in the Middle East: Origins, Transmission, Treatment, and Perspectives
نویسندگان
چکیده
Two years have passed since the initial description of the Middle East respiratory syndrome coronavirus (MERS-CoV), yet the epidemic is far from being controlled. The high case fatality rate, the recent steep increase in reported cases, and the potential to cause a global pandemic during the upcoming Hajj season are serious concerns. Although a wealth of information about the pathophysiology, proposed animal reservoir, and intermediate host has been revealed, many questions remain unanswered. We herein review MERS-CoV, covering its proposed origins, route of transmission, treatment options, and future perspectives.
منابع مشابه
Genetics and epidemiology of Middle East Respiratory Syndrome-Coronavirus (MERS-CoV)
Background and aims: Middle East respiratory syndrome (MERS) is a viral respiratory illness caused by a coronavirus. After the primary onset of MERS in Saudi Arabia, in September 2015 cases began to increase. The number of laboratory-affirmed cases by MERS-CoV in the Middle East has been being increased recently. Methods: In this current review article, by using the terms “MERS” and “coronavir...
متن کاملMiddle East Respiratory Syndrome Coronavirus (MERS-CoV): A Review Article
The recently emerged Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in the Middle East region in 2012. The virus is phylogenetically related to bat CoV, but other animal species like camels and goats may potentially act as an intermediate host by spreading the virus to humans. This virus is thought to cause a severe disease in patients with underlying comorbidities. Laboratory ...
متن کاملMiddle East respiratory syndrome coronavirus: epidemiology and disease control measures
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in 2012 resulted in an increased concern of the spread of the infection globally. MERS-CoV infection had previously caused multiple health-care-associated outbreaks and resulted in transmission of the virus within families. Community onset MERS-CoV cases continue to occur. Dromedary camels are currently the most ...
متن کاملConcerns about Misinterpretation of Recent Scientific Data Implicating Dromedary Camels in Epidemiology of Middle East Respiratory Syndrome (MERS)
This letter addresses some concerns about two recent articles published by the same authors in mBio (1, 2), specifically many uncertainties regarding the potential applicability of their epidemiological data, which were obtained from dromedary camels (DCs) infected with Middle East respiratory syndrome coronavirus (MERS-CoV), to human public health. Aiming to investigate the possible role of DC...
متن کاملMiddle East respiratory syndrome in children
As of January 2016, 1,633 laboratory-confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection and 587 MERS-related deaths have been reported by the World Health Organization globally. Middle East Respiratory Syndrome Coronavirus may occur sporadically in communities or may be transmitted within families or hospitals. The number of confirmed MERS-CoV cases among heal...
متن کامل